What is CCM® Therapy?
Cardiac Contractility Modulation Therapy is a new therapeutic approach that improves quality of life for patients that are no longer adequately responding to medications intended to manage symptoms or slow the progression of heart failure.
How Do We Treat Chronic Heart Failure?
If you are diagnosed with heart failure, you’ll need lifelong management for the condition. Although treatment of CHF depends on its cause, it’s typically treated with drugs and/or implanted devices such as implantable cardiac defibrillators or cardiac resynchronization devices.
These treatments don’t always result in an improvement of symptoms for all patients. That’s why we’ve developed the Optimizer® Smart Mini; to help you find relief even when traditional approaches prove minimally effective, and other treatments aren’t yet applicable.
Is It Right For You?
CCM® Therapy was invented to help patients diagnosed with moderate to severe heart failure.
Have you been diagnosed with chronic heart failure? If so, your current therapy may include pharmaceuticals such as water pills or beta-blockers and you may not qualify for additional therapies such as Cardiac Resynchronization Therapy.
You may feel your medication is the only treatment you have access to. Although once true, with CCM® Therapy delivered by the Optimizer® Smart Mini, it’s now possible to experience relief from moderate to severe heart failure and gain your life back.
The Optimizer® Smart Mini: Improving Your Day-to-Day Life
The Optimizer® Smart Mini is designed to increase the strength of your heart’s contractions. The therapy you’ll receive may diminish the symptoms of CHF, allowing you to take your life back. Walking, climbing steps, and playing with your kids or grandkids could become easier due to the reduction in the need to rest after performing simple activities.
This device has already improved the lives of thousands of patients struggling with the symptoms of CHF.
How Does the Optimizer® Smart Mini Work?
The Optimizer® Smart Mini is a minimally invasive implantable device designed to improve contraction of the heart, allowing more oxygen-rich blood to reach the body. It delivers precisely timed electrical pulses to the heart cells during a special period of the beating cycle (called the absolute refractory period, or the period just after the heart contracts). In doing so, it strengthens and helps the heart more forcibly, thereby delivering more blood and oxygen to the body.
Studies have shown CCM® Therapy to improve 6-minute hall walk distance, quality of life and functional status among patients who are candidates for the device.
What is the Procedure?
The Optimizer® Smart Mini device is similar in size to a pacemaker and is implanted during a minimally invasive procedure while the patient is under light sedation. During the procedure, the device is implanted under the skin of the upper chest, along with electrical leads that are placed in the heart’s right ventricle through the veins. After the procedure, the physician programs the delivery of CCM® Therapy for each patient and activates the device. The implanted device then sends precisely calibrated and timed electrical pulses to the heart muscle during one-hour treatment periods scheduled intermittently throughout the day.
From the comfort of their home, the patient charges the device each week for one hour using an external charger. The Optimizer® Smart Mini has been rigorously tested and it is expected to provide CCM® Therapy for up to 20 years before requiring replacement.
Testimonials
Clinical Evidence
Evidence from clinical and bench investigations suggest that CCM® Therapy improves the heart’s contractility, as it is designed to do so, by modifying the function and expression of proteins in the heart muscle.
Clinical trials have demonstrated statistically significant and clinically meaningful improvements in the FIX-HF-5C randomized trial:
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- CCM® subjects improved 11.7 points in the MLWHFQ score compared to the control group
- CCM® subjects improved their NYHA heart failure status by >1 class 81% of the time compared to 42% in the control group
- CCM® subjects walked on average 33.7 meters further than the control group during the 6-minute hall walk test
